Article ID Journal Published Year Pages File Type
10972107 Fish & Shellfish Immunology 2012 6 Pages PDF
Abstract
► An flounder Hsp70 homologue, PoHsp70, exhibited ATPase activity as a recombinant protein. ► PoHsp70M, which bears mutation of the ATPase domain, was abolished in activity. ► Expression of PoHsp70 was induced by vaccination with a DNA vaccine. ► PoHsp70 and PoHsp70M were each co-expressed with a DNA vaccine. ► PoHsp70, but not PoHsp70M, significantly increased the protection of the DNA vaccine.
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Life Sciences Agricultural and Biological Sciences Aquatic Science
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