| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10972113 | Fish & Shellfish Immunology | 2012 | 13 Pages |
Abstract
⺠Two duplicated type I interferon genes have been identified in rock bream. ⺠They belong to subgroup-d of two cysteine containing IFNs and are orthologous to zebrafish IFNÏ4. ⺠The expression of two IFNs showed significant induction upon challenge with different immune stimuli in blood and head kidney. ⺠The rbIFN1 produced in E. coli showed bioactivity of inducing Mx gene expression. ⺠Two IFNs are involved in in rock bream host response to both viral and bacterial pathogens.
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Authors
Qiang Wan, W.D. Niroshana Wicramaarachchi, Ilson Whang, Bong-Soo Lim, Myung-Joo Oh, Sung-Ju Jung, Hyun Chul Kim, Sang-Yeob Yeo, Jehee Lee,