| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1254104 | Chinese Chemical Letters | 2014 | 5 Pages |
Abstract
A substitution reaction of amines with alcohols for N-alkylated amines has been developed using inexpensive AlCl3 without any ligand or additive. Either aromatic or aliphatic amines and primary or secondary alcohols perform the AlCl3-mediated reaction smoothly to afford various N-alkylated amines in satisfactory yields.
Graphical abstractA direct N-alkylation of amines with alcohols has been developed using AlCl3 as a Lewis acid. Either aromatic or aliphatic amines and primary or secondary alcohols perform the AlCl3-mediated reaction smoothly to afford various N-alkylated amines.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Ya-Qiong Li, Yun-Bin Chen, Zhi-Zhen Huang,