A new green approach for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthene-11-one derivatives using task specific acidic ionic liquid [NMP]H2PO4

12-Aryl-8,9,10,12-tetrahydrobenzo[a]xanthene-11-one derivatives were synthesized by a convenient and environmentally benign procedure involving multicomponent condensation reactions of substituted aromatic aldehydes with 2,7-dihydroxynaphthalene/2-naphthols/2,6-dihydroxynaphthlene and cyclic 1,3-dicarbonyl compounds in task specific acidic ionic liquid [NMP]H2PO4 at 80 °C. This protocol has proved to be efficient in terms of good yields, operational simplicity, easy workup, recyclability of reaction medium/catalyst, and short reaction time.

Graphical abstractNew efficient and green synthesis of benzo[a]xanthene derivatives in NMP[H2PO4] is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide