| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1254274 | Chinese Chemical Letters | 2013 | 4 Pages |
Abstract
A series of hydrazone and N-acylhydrazone derivatives of dehydroabietic acid were synthesized and evaluated for BK channel-opening activities in an assay system of CHO-K1 cells expressing hBKα channels. The assay results indicated that the activities of the investigated compounds were influenced by the physicochemical properties of the substituent at hydrazone moiety.
Graphical abstractA series of hydrazone (2) and N-acylhydrazone derivatives (3) of dehydroabietic acid were synthesized and evaluated for BK channel opening activities in an assay system of CHO-K1 cells expressing hBKα channels.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Xia-Shi Lv, Yong-Mei Cui, He-Yun Wang, Hai-Xia Lin, Wei-Ya Ni, Tomohiko Ohwada, Katsutoshi Ido, Kohei Sawada,