| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1254403 | Chinese Chemical Letters | 2015 | 6 Pages |
WS2 nanosheets were prepared by the solvent-thermal method in the presence of n-butyl lithium, then the exfoliation under the condition of ultrasound. The formed WS2 nanosheets were conjugated with thiol-modified polyethylene glycol (PEG-SH) to improve the biocompatibility. The nanosheets (WS2-PEG) were able to inhibit the growth of a model HeLa cancer cell line in vitro due to the high photothermal conversion efficiency of ∼35% irradiated by an 808 nm laser (1 W/cm2). As a proof of concept, WS2-PEG nanosheets with the better X-ray attenuation property than the clinical computed tomography (CT) contrast agent (Iohexol) could be performed for CT imaging of the lymph vessel.
Graphical abstractThe WS2-PEG nanosheets have the high photothermal conversion efficiency and show a good X-ray attenuation property.Figure optionsDownload full-size imageDownload as PowerPoint slide
