Article ID Journal Published Year Pages File Type
1254437 Chinese Chemical Letters 2012 4 Pages PDF
Abstract

An efficient green protocol is described for the preparation of highly functionalized piperidines via a one-pot five-component reaction between aromatic aldehydes, anilines and β-ketoesters in the presence of oxalic acid dihydrate as catalyst in ethanol at ambient temperature. The structure as well as the relative stereochemistry of these compounds was confirmed by single X-ray crystallographic analysis.

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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