| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1254570 | Chinese Chemical Letters | 2016 | 4 Pages |
Abstract
We have explored the chemistry of N-oxide heterocycles and imidazoles replacing ring D of the natural product (+)-calanolide A, and have synthesized 12 new analogues, two of which were active against both R Mtb and NR Mtb with MIC values of 12.5 μg/mL, which would lead to further optimization for more potent anti-TB candidates.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Zi-Jie Liu, Xiao-Yong Guo, Gang Liu,