Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1254582 | Chinese Chemical Letters | 2016 | 5 Pages |
Abstract
A catalyst- and solvent-free protocol for the synthesis of 7-azagramine analogues is described via a three-component Mannich type reaction between 7-azaindole, aromatic aldehydes and heterocyclic amines in acceptable to excellent yields. Structures of the compounds were confirmed satisfactorily by 1H NMR, IR, mass, TOCSY, HSQC and HMBC spectral analyses.
Graphical abstractA catalyst- and solvent-free protocol for the synthesis of 7-azagramine analogues via a three-component Mannich type reaction is described.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
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Chemistry (General)
Authors
Sakharam B. Dongare, Hemant V. Chavan, Pravin S. Bhale, Yoginath B. Mule, Amol S. Kotmale, Babasaheb P. Bandgar,