Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1254585 | Chinese Chemical Letters | 2016 | 5 Pages |
This paper describes a very simple, efficient synthesis of quinazolinones and chromeno[d]pyrimidinones from the reaction of aryl aldehydes, urea/thiourea and active methylene compounds (dimedone/4-hydroxycoumarin) using nano-sized CuI particles under solvent-free conditions. The highlights of this new method are based on using an effective and recyclable catalyst, affording high yields of products, mild reaction conditions, facile work-up and purification.
Graphical abstractA very simple and efficient catalytic protocol for the synthesis of quinazolinones and chromeno[d]pyrimidinones is reported using nano-sized CuI particles as an efficient heterogeneous catalyst under solvent-free conditions.Figure optionsDownload full-size imageDownload as PowerPoint slide