| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1254762 | Chinese Chemical Letters | 2011 | 4 Pages |
Abstract
Three model drugs with different function groups were chosen to dialyze with dextran-graft-poly (N-isopropylacrylamide). Only ibuprofen could induce the formation of drug loaded micelles, which was confirmed with dynamic light scattering and transmission electron microscope. Hydrogen-bonding between the amide groups of poly (N-isopropylacrylamide) and the carboxyl groups of ibuprofen was driving force for the drug-loaded micelle. It was also found that the diameter of the ibuprofen-loaded micelles changed reversibly against temperature.
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Authors
Song Wei Tan, Hong Jun Wang, Ke Hua Tu, Hong Liang Jiang, Li Qun Wang,