Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1254811 | Chinese Chemical Letters | 2014 | 5 Pages |
Abstract
Silica-bonded N-propyl sulfamic acid (SBNPSA) catalyzed one-pot three component Biginelli condensation of different substituted aromatic aldehydes with ethyl acetoacetate and urea/thoiurea to the respective 3,4-dihydropyrimidin-2-(1H)-ones and thiones in environment friendly procedure is described. The facile reaction conditions, simple isolation and purification procedures of this method make it a good option for the synthesis of dihydropyrimidinones.
Graphical abstractSilica-bonded N-propylenesulfamic acid catalyzed Biginelli reaction was studied.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Srinivasa Rao Jetti, Anjna Bhatewara, Tanuja Kadre, Shubha Jain,