Article ID Journal Published Year Pages File Type
1254811 Chinese Chemical Letters 2014 5 Pages PDF
Abstract

Silica-bonded N-propyl sulfamic acid (SBNPSA) catalyzed one-pot three component Biginelli condensation of different substituted aromatic aldehydes with ethyl acetoacetate and urea/thoiurea to the respective 3,4-dihydropyrimidin-2-(1H)-ones and thiones in environment friendly procedure is described. The facile reaction conditions, simple isolation and purification procedures of this method make it a good option for the synthesis of dihydropyrimidinones.

Graphical abstractSilica-bonded N-propylenesulfamic acid catalyzed Biginelli reaction was studied.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
Authors
, , , ,