Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1254831 | Chinese Chemical Letters | 2011 | 4 Pages |
Abstract
The asymmetric aza-Henry reaction of α-substituted nitroacetates and N-Boc imines was achieved with a new-type thiourea-guanidine bifunctional organocatalyst. The novel transformations exhibited high diastereoselectivities, and the adducts bearing adjacent quaternary and tertiary chiral centers were generally obtained in moderate to good enantioselectivities (up to 88% ee).
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Bo Han, Wei Huang, Zhen Rui Xu, Xiao Ping Dong,