| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1254926 | Chinese Chemical Letters | 2010 | 4 Pages |
Abstract
A series of novel derivatives of indirubin were synthesized and evaluated for their anti-proliferative activity against human cancer cell lines of SGC7901, A549, HL-60, SK-BR-3 and HCT116. Most of the compounds displayed more potent activity than Sunitinib. In addition, the derivatives showed improved water solubility, which may be favorable to their pharmacokinetic performances.
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Authors
Tian Cai Wang, Ju Zhi Wei, Chuan Sheng Guo, Hui Bin Zhang, Hou Xing Fan,