| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1255123 | Chinese Chemical Letters | 2012 | 5 Pages |
Abstract
The mechanism for synthesis of 4,4-methylenedianiline (MDA) via condensation reaction of aniline with formaldehyde has been studied extensively in this paper. The intermediate and by-products were isolated and identified. The combination of isotope labeling and HPLC–MS characterizations disclosed that the reaction proceeded through an SN2 reaction mechanism. Moreover, the effect of aniline/formaldehyde molar ratio on the formation of MDA was investigated. This work would be of significance to understand the reaction mechanism deeply and provide valuable information for further improving the yield of desired product.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Chen Ye Wang, Hui Quan Li, Li Guo Wang, Yan Cao, Hai Tao Liu, Yi Zhang,