| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1255159 | Chinese Chemical Letters | 2012 | 4 Pages |
Abstract
A new sesquiterpenoid, 1β,5α-guaiane-4β,10α-diol-6-one (1), was isolated from 70% EtOH extract of the rhizomes of Acorus calamus. The structure was determined on spectroscopic methods, especially 2D NMR techniques. The absolute configuration of 1 was confirmed by TDDFT quantum chemical calculation of its ECD spectrum. Compound 1 showed promising anti-diabetic activity on a insulin-mediated glucose consumption model of HepG2 cells.
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Authors
Chang Xin Zhou, Di Qiao, You You Yan, Hao Shu Wu, Jian Xia Mo, Li She Gan,