| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1255306 | Chinese Chemical Letters | 2009 | 4 Pages |
Abstract
In order to find compounds with superior bioactivity and overcoming multidrug resistance, a novel series of 4β-N-substituted podophyllotoxin derivatives were synthesized and evaluated as potential antitumor agents. Seven novel podophyllotoxin derivatives were synthesized by linking 4β-amino-4-deoxypodophyllotoxin with alcohols through maleic acid and tested against K562 and K562/A02 using MTT assay in vitro.
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Authors
Ming Zhao, Min Feng, Shu Fang Bai, Yuan Zhang, Wen Chao Bi, Hong Chen,