Article ID Journal Published Year Pages File Type
1255308 Chinese Chemical Letters 2009 4 Pages PDF
Abstract

An efficient synthesis of 3,4-dihydropyrimidine 2 (1H)-ones and thiones (3,4-DHPMs) core was prepared by one-pot three-component Biginelli condensation and which was catalyzed by trifluoromethane sulfonic acid. The classical Bignelli reaction has been extended by the use of N-substituted benzoxazolyl semicarbazides and thiosemicarbazides and this method has the advantage of excellent yields and short reaction times.

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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