Electrochemical behavior of Ru(H2bpp)2(PF6)2 and its interaction with bovine serum albumin (BSA)

In this paper, it was found that Ru(H2bpp)2(PF6)2 (H2bpp = 2,6-bis(pyrazol-3-yl)pyridine) complex had excellent electrochemical activity at the carbon paste electrode in the buffer solution of Tris-HCl (pH 7.0) with a couple reversible redox peaks at 0.296 V and 0.348 V, respectively. Voltammetry was used to investigate the electrochemical behavior of Ru(H2bpp)2(PF6)2 and the interaction between Ru(H2bpp)2(PF6)2 and bovine serum albumin (BSA). In the present of BSA, the oxidation peak current of Ru(H2bpp)2(PF6)2 complex was decreased linearly and the decrease of oxidation peak current of Ru(H2bpp)2(PF6)2 is proportional to BSA concentration from 0.1 to 2.5 mg/L with a detection limit 0.02 mg/L.