| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1255591 | Chinese Chemical Letters | 2012 | 4 Pages |
Abstract
(R)-2-Chloro-1-(m-chlorophenyl)ethanol, a precursor of (R)-3-chlorostyrene oxide which is the key chiral intermediate for the preparation of several β3-adrenergic receptor agonists was prepared in 40% yield and 99% ee by the Lipozyme TL IM-catalyzed second resolution of the corresponding racemate in the presence of vinyl acetate.
Related Topics
Physical Sciences and Engineering
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Chemistry (General)
Authors
Shi Wen Xia, Hui Lin, Yong Zheng Chen,