Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1255596 | Chinese Chemical Letters | 2012 | 4 Pages |
Abstract
Cross double Mannich reaction and tandem cyclization were achieved under iodine catalyzed conditions, yielding a series of highly substituted 4-piperidones. Among the possible diastereomers, only one diastereomer was isolated, which could be ascribed to the chair-like transition state in six-membered ring, in which all of the hindered groups are located in the pseudoequatorial orientation.
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Authors
Xiao Dong Jia, Xiang Ning Chen, Cong De Huo, Fang Fang Peng, Chang Qing, Xi Cun Wang,