| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1255597 | Chinese Chemical Letters | 2012 | 4 Pages |
Abstract
Canrenone (1) was biotransformed into 11α-hydroxycanrenone (2) and a main byproduct (3) by Aspergillus ochraceus SIT34205. Compound 3 was separated and purified using silica gel column chromatography, and its structure was characterized via MS and NMR methods. These results indicated that 3 was 1β,11α-dihydroxycanrenone and the product of further hydroxylation of 2. Thus, investigating the structure and synthesis of 3 may be a promising method to improve the efficiency and purity of 2.
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Authors
Shao Feng Rong, Xiao Li Zhang, Bao Mei Ding, Yi Fei Wang, Xian Hua Pan, Jian Zhang, Yi Shen,