Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1255774 | Chinese Chemical Letters | 2008 | 4 Pages |
Abstract
A series of new O6-BG derivatives (14–21,23–30) were synthesized as inactivators of O6-Alkylguanine-DNA alkyltransferase (AGT), and their ability to inhibit AGT was preliminary evaluated by MTT with O6-BG as the control. The result suggested compound 30 displayed a higher activity than O6-BG.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Lei Zhang, Bing Jia, Chang Feng Hu, Fan Wang, Yu Xin Cui,