Article ID Journal Published Year Pages File Type
1255774 Chinese Chemical Letters 2008 4 Pages PDF
Abstract

A series of new O6-BG derivatives (14–21,23–30) were synthesized as inactivators of O6-Alkylguanine-DNA alkyltransferase (AGT), and their ability to inhibit AGT was preliminary evaluated by MTT with O6-BG as the control. The result suggested compound 30 displayed a higher activity than O6-BG.

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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