Article ID Journal Published Year Pages File Type
1255821 Chinese Chemical Letters 2010 4 Pages PDF
Abstract

A new derivative of triterpene named Erigeronol 1 was isolated from the EtOH extract of the aerial part of Conyza canadensis together with 15 known compounds for the first time from this plant. The structure of Erigeronol 1 was elucidated as 3-O-(hydroxy-acetyl)-23,28-dihydroxy-β-amyrin by hydrolysis and spectroscopic analysis. Erigeronol 1 showed potent cytotoxic activity with IC50 value of 7.77 ± 0.47 μg/mL against melanoma B16 determined by the 3-(4,5-dimethylthiazo-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method.

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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