Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1255843 | Chinese Chemical Letters | 2011 | 4 Pages |
Abstract
Asymmetric conjugated addition of allylcopper reagents derived from an allyl Grignard reagent and CuBr·Me2S to chiral α,β-unsaturated N-acyl oxazolidinones has been achieved. The synthetic procedure was applied to the preparation of the key intermediate of the novel nonbenzodiazepine hypnotic drug, ramelteon.
Related Topics
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Authors
Shan Bao Yu, Hao Min Liu, Yu Luo, Wei Lu,