Article ID Journal Published Year Pages File Type
1255856 Chinese Chemical Letters 2011 4 Pages PDF
Abstract

An efficient 1-methylimidazole-catalyzed synthesis of dialkyl 2-[(4-methylphenyl)sulfonyl]-1H-pyrrole-3,4-dicarboxylates is described. The reactive 1:1 zwitterionic intermediate formed by the addition of 1-methylimidazole to dialkyl acetylenedicarboxylates is trapped by tosylmethyl isocyanide (TOSMIC) to afford the title compounds in excellent yields.

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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