| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1255887 | Chinese Chemical Letters | 2010 | 4 Pages |
Abstract
A series of new 6,7-disubstituted-4-(benzothiazol-6-ylamino)quinoline-3-carbonitrile derivatives (12a–l) were synthesized. The cytotoxicity of 12 new compounds was evaluated in AGS, HepG2 and HT-29 cell lines. The results showed that compounds 12g, 12h, 12i, 12k and 12l displayed more potent cytotoxic activities than Bosutinib, compound 12l exhibited the most potent antitumor activity among the tested compounds.
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Authors
Bao Liu, Qi Dong You, Zhi Yu Li,