Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1256113 | Chinese Chemical Letters | 2007 | 4 Pages |
Abstract
An efficient synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives using formic acid as catalyst, from aldehydes, β-ketoester and urea(thiourea) without solvent under the irradiation of microwave is described. Compared with the classical Biginelli reaction, this new method has the advantage of good yields (77–94% for aromatic aldehydes) and short reaction time (3–8 min).
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Cheng Jiang, Qi Dong You,