Article ID Journal Published Year Pages File Type
1256397 Chinese Chemical Letters 2007 4 Pages PDF
Abstract

An ss-DNA gold chip was prepared based on self-assembly of the thiol-derivatized oligonucleotide, and used for the determination of single-stranded binding protein (SSB) by surface plasmon resonance microscopy (SPR). The experiment results showed that SSB binds ss-DNA with high specificity, and relative signal of SPR response is proportional to the concentration of SSB in the range of 0.1–100 ng/mL with a detection limit (S/N = 3) of 0.07 ng/mL.

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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