Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1256416 | Chinese Chemical Letters | 2008 | 4 Pages |
Abstract
A series of 2,4,5-triaryl substituted 1H-pyrazol-3(2H)-ones, as ALK5 inhibitors, were desigened, synthesized and evaluated in vitro. Most compounds exhibited noticeable ALK5 inhibition activities at 1 μmol/L and displayed no significant cytotoxicities at 30 μmol/L.
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Xing Zhou Li, Xian Ping Dai, Kang Ying Lai, Li Li Wang, Zhi Bing Zheng, Song Li,