| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1256870 | Chinese Chemical Letters | 2015 | 4 Pages |
A method of C(sp3)H bond functionalization of methyl azaarenes catalyzed by alumina-supported heteropoly acid and addition to isatins was developed. This transformation could be used for the synthesis of biologically important 3-hydroxy-2-oxindole derivatives in good to excellent yields and the catalyst could be reused for six times without significant decrease in activity.
Graphical abstractC(sp3)H bond functionalization of methyl azaarenes catalyzed by alumina-supported heteropoly acid and nucleophilic addition to isatins was developed. This transformation could be used for the synthesis of bioactive 3-hydroxy-2-oxindole derivatives in good to excellent yields and the catalyst could be reused for six times without significant decrease in activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
