Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1256957 | Chinese Chemical Letters | 2015 | 5 Pages |
A new highly efficient and reusable Cu(I)-MOF has been developed for the synthesis of propargylamine compounds via the three-component reaction of secondary amines, alkynes, and aromatic aldehydes under solvent-free conditions. The desired propargylamines were obtained in good to excellent yields with a low catalyst loading. The catalyst may be recovered and reused for up to 5 cycles without major loss of activity. This protocol has the advantages of excellent yields, low catalyst loading, and catalyst recyclability.
Graphical abstractA highly efficient and reusable Cu(I)-MOF has been developed for the synthesis of propargylamine compounds through the three-component reaction of secondary amines, alkynes, and aromatic aldehydes under neat conditions.Figure optionsDownload full-size imageDownload as PowerPoint slide