Article ID Journal Published Year Pages File Type
1256957 Chinese Chemical Letters 2015 5 Pages PDF
Abstract

A new highly efficient and reusable Cu(I)-MOF has been developed for the synthesis of propargylamine compounds via the three-component reaction of secondary amines, alkynes, and aromatic aldehydes under solvent-free conditions. The desired propargylamines were obtained in good to excellent yields with a low catalyst loading. The catalyst may be recovered and reused for up to 5 cycles without major loss of activity. This protocol has the advantages of excellent yields, low catalyst loading, and catalyst recyclability.

Graphical abstractA highly efficient and reusable Cu(I)-MOF has been developed for the synthesis of propargylamine compounds through the three-component reaction of secondary amines, alkynes, and aromatic aldehydes under neat conditions.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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