Chromogenic and fluorescent “turn-on” chemodosimeter for fluoride based on F−-sensitive self-immolative linker

A new chromogenic and fluorescent “turn-on” chemodosimeter 3 was designed and synthesized by using a fluoride-sensitive self-immolative linker, in combination with the fluorescent dyes 7-hydroxy-4-trifluoromethyl coumarin. The chemodosimeter exhibited high selectivity and sensitivity toward fluoride anions through “turn-on” chromogenic and fluorogenic dual modes.

Graphical abstractA novel fluorescent chemosensor containing 7-hydroxy-4-trifluoromethyl coumarin was developed for sensing of fluoride based on F−-sensitive self-immolative linker.Figure optionsDownload full-size imageDownload as PowerPoint slide