Synthesis of indol-3-yl aryl ketones through visible-light-mediated carbonylation

A visible-light-catalyzed synthesis of indol-3-yl aryl ketones from aryldiazonium salts, CO and indoles at room temperature was developed. This process provides a useful method for the preparation of diverse indol-3-yl aryl ketones from readily accessible reactants under base-free, acid-free and transition-metal-free conditions.

Graphical abstractA visible-light-catalyzed synthesis of indol-3-yl aryl ketones from aryldiazonium salts, CO and indoles at room temperature under acid-free, base-free and metal-free conditions was described.Figure optionsDownload full-size imageDownload as PowerPoint slide