Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1257069 | Chinese Chemical Letters | 2013 | 4 Pages |
Abstract
Tetrazole-1-acetic acid was found to serve as a superior ligand for CuI-catalyzed N-arylation of imidazoles with aryl iodides under a low catalyst loading (5 mol% of CuI). A variety of aryl iodides could be aminated to provide the N-arylated products in good to excellent yields without the need of an inert atmosphere.
Graphical abstractAn experimentally simple and inexpensive catalyst system was developed for the N-arylation of imidazoles with aryl iodides by applying CuI as catalyst, tetrazole-1-acetic acid as ligand, NaOH as base and DMSO as solvent.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Feng-Tian Wu, Ping Liu, Xiao-Wei Ma, Jian-Wei Xie, Bin Dai,