SnCl2/nano SiO2: A green and reusable heterogeneous catalyst for the synthesis of polyfunctionalized 4H-pyrans

A highly efficient and general method for the synthesis of polyfunctionalized 4H-pyrans is established through a one-pot multicomponent cyclocondensation of aromatic aldehydes with CH acids, malononitrile and ethyl acetoacetate using nano silica supported tin (II) chloride as a catalyst. In this method SnCl2/nano SiO2 was used as green and reusable catalyst. Excellent yields, short reaction times, simple workup, and inexpensiveness and commercially availability of the catalyst are the advantages of this method.

Graphical abstractHeterogeneous SnCl2/nano SiO2 catalyzed the preparation of polyfunctionalized 4H-pyrans in high yields and simple workup procedures.Figure optionsDownload full-size imageDownload as PowerPoint slide