Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1257370 | Chinese Chemical Letters | 2012 | 4 Pages |
Abstract
An antimetastatic tetrasaccharide T1, β-d-Gal-(1 → 4)-β-d-GlcpNAc-(1 → 6)-α-d-Manp-(1 → 6)-β-d-Manp-OMe, was synthesized with two approaches. The first approach was a conventional method employing thioglycoside and Koenigs–Knorr glycosylation reaction in 24% overall yield. The second one was a novel route through the azidoiodo-glycosylation strategy by using 2-iodo-2-deoxylactosyl azide as the donor in 36% overall yield.
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Kai Jun Liao, Xiao Feng Jin, Xiang Bao Meng, Chen Li, Zhong Jun Li,