Article ID Journal Published Year Pages File Type
1257480 Chinese Chemical Letters 2012 5 Pages PDF
Abstract

Five triorganotin(IV) (1–5) complexes of cinnamic acid, (Z)-2-acetamido-3-phenylacrylic acid, 3-methylbut-2-enoic acid, and 2,2-diphenylacetic acid have been synthesized and characterized by 1H–13C–119Sn NMR, UV, and IR. The spectroscopic investigation demonstrated that the carboxylate group acts as a monodentate ligand in triorganotin(IV) compounds. Five triorganotin(IV) complexes were screened against the log phase culture of Mycobacterium tuberculosis H37Rv by colorimetric method using XTT dye as growth indicator. The MICs were found to be 0.08 and 1.25 μg/mL.

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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