| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1257581 | Chinese Chemical Letters | 2012 | 4 Pages |
Abstract
This research presented an annealing strategy to identify hairpin DNA from coil DNA with the same base composition but different arrangements using electrospray mass spectrometry (ESI-MS). A series of single-stranded DNA were annealed with their complementary sequences, respectively. All the five pairs of hairpin DNA and coil DNA were unambiguously distinguished by ESI-MS with annealing strategy. This research offers a potential method to probe the DNA structure by comparing with mass spectral characteristics.
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Authors
Bo Zheng, Yi Quan Liu, Gu Yuan,