| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1257652 | Chinese Chemical Letters | 2011 | 4 Pages |
Abstract
A combination of tetrachlorosilane (TCS) and phenol in dichloromethane was found to be an efficient reagent for hydrochlorination of α,β-unsaturated ketones to afford the corresponding β-chloroketones in good yield at ambient temperature. Reactions of the titled compounds with TCS-NaN3 as well as with nitriles utilizing TCS-ZnCl2 to give 1,5-disubstituted tetrazole derivatives or β-amido ketones respectively are also described.
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Authors
Tarek A. Salama, Saad S. Elmorsy,