Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1257685 | Chinese Chemical Letters | 2011 | 4 Pages |
Abstract
A series of 3-ethoxy-4-hydroxybenzylidene/4-nitrobenzylidene hydrazides (1–20) was synthesized and tested for in vitro antimicrobial activity. The results of antimicrobial studies indicated that the compounds having dinitro, methoxy, hydroxy and nitro substituents on phenyl ring of the aromatic acids were most active ones. The QSAR investigation indicated the importance of the topological parameter, third order molecular connectivity index (3χ) in describing the antimicrobial activity of synthesized hydrazides.
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Davinder Kumar, Archana Kapoor, Ananda Thangadurai, Pradeep Kumar, Balasubramanian Narasimhan,