| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1257734 | Chinese Chemical Letters | 2010 | 4 Pages |
Abstract
New D-seco-taxoids were synthesized from 1-deoxybaccatin VI and their structures were confirmed by 1H NMR, 13C NMR, ESIMS and X-ray crystallography. The key step of the synthesis involved the opening of the oxetane ring under acid and basic conditions in order to obtain new multidrug resistance (MDR) reversal agents and new synthetic precursors of paclitaxel analogues.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Jun Chao Shao, Zhi Hua Ye, Hai Xia Lin, Dian Long Wang, Na Han,