Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1257735 | Chinese Chemical Letters | 2010 | 4 Pages |
Abstract
A simple, highly effective hydrogenation of chiral BINOL to provide H4-BINOL in multigram scale with good yield (up to 78% yield) was developed. A series of heterogeneous catalysts was tested in the hydrogenation; the best result was obtained with 5% Pd/C in EtOH under the H2 pressure of 50 bar for 2 h. This method is a more useful method for practical synthesis of optically pure H4-BINOL than other available methods.
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Qian Chang Ding, Yun Feng Du, Xin Sheng Li, Dong Cheng Xu,