Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1257740 | Chinese Chemical Letters | 2010 | 4 Pages |
Abstract
A series of novel coumarin–stilbenes hybrids called 3-arylcoumarins were synthesized via Perkin reaction and evaluated as potential antitumor agents. The results showed that some compounds exhibited in vitro activity against KB, KV, MCF-7, MCF-7/ADR cell lines to some extent. Compound 3a showed remarkable effect against KB tumor cells with an IC50 value of 5.18 μmol/L.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Chun Fen Xiao, Li Yang Tao, Hong Yi Sun, Wen Wei, Yu Chen, Li Wu Fu, Yong Zou,