Article ID Journal Published Year Pages File Type
1257740 Chinese Chemical Letters 2010 4 Pages PDF
Abstract

A series of novel coumarin–stilbenes hybrids called 3-arylcoumarins were synthesized via Perkin reaction and evaluated as potential antitumor agents. The results showed that some compounds exhibited in vitro activity against KB, KV, MCF-7, MCF-7/ADR cell lines to some extent. Compound 3a showed remarkable effect against KB tumor cells with an IC50 value of 5.18 μmol/L.

Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
Authors
, , , , , , ,