| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1257749 | Chinese Chemical Letters | 2010 | 4 Pages |
Abstract
A series of 1H-benzimidazol-5-ol derivatives were synthesized and evaluated for their anti-hepatitis B virus (HBV) activity and cytotoxicity in HepG2.2.15 cells. Half of the tested compounds were found to be potent against HBsAg secretion with IC50 values less than 100 μmol/L. Compounds 14c, 14d, and 14e showed significant inhibitory activity to the viral antigen HBeAg.
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Dong Chen, Xin Zhai, Qiu Hui Yuan, Jian Luo, Si Chang Xie, Ping Gong,