Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1257786 | Chinese Chemical Letters | 2011 | 4 Pages |
Abstract
A new and simple capillary electrophoresis with electrochemiluminescence detection was developed for the separation and the quantification of a pair of diastereoisomeric alkaloids (ephedrine and pseudoephedrine). The limits of detection (S/N = 3) were 4.5 × 10−8 mol/L for ephedrine and 5.2 × 10−8 mol/L for pseudoephedrine, respectively. The RSDs of migration time and peak area were less than 1.3 and 2.5% (n = 5), respectively. The applicability of the propose method was illustrated in the determination of ephedrine and pseudoephedrine in human urine, ephedrine in nasal drops, and the monitoring of pharmacokinetics for pseudoephedrine.
Related Topics
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Authors
Yan Ming Liu, Long Fei Peng, Lin Mei, Li Juan Liu,