Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1257851 | Chinese Chemical Letters | 2010 | 4 Pages |
Abstract
Gold nanoparticles (GNPs) have been widely used as probes and nanomaterials in certain biological and biomedical fields thanks to its special physical and chemical properties. However, it is still difficult to characterize GNPs-bioconjugates in solution, which has greatly limited further bioapplications of GNPs. In this study, we reported a single particle method for characterizing GNPs-biomolecules in solution using resonance light scattering correlation spectroscopy (RLSCS). The interaction of GNPs with bovine serum albumin (BSA) and thiol-modified oligonucletides were investigated.
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Authors
Xin Qiu, Li Chuan Tang, Chao Qing Dong, Ji Cun Ren,