An efficient synthesis of pyrazole chalcones under solvent free conditions at room temperature

An easy, safe, solvent free and effective method for the synthesis of pyrazole-substituted chalcones has been achieved by grinding pyrazole aldehydes and acetophenones in the presence of activated barium hydroxide (C-200) in high yield within short span of time. All reactions were carried out just by grinding the two reactants in the presence of activated barium hydroxide (C-200). Results are also compared with sodium hydroxide and potassium hydroxide.