| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1257881 | Chinese Chemical Letters | 2011 | 4 Pages |
Abstract
A new series of benzamide derivatives as glucokinase activators (GKAs) were designed and synthesized, and their activation for glucokinase were evaluated by the preliminary glucokinase activity assay. The structure–activity relationship (SAR) is discussed. The result shows that compound 12d and 12h have potent activity reference drug RO-28-1675.
Related Topics
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Chemistry
Chemistry (General)
Authors
Yong Qiang Li, Yu Liang Zhang, Sheng Quan Hu, Yu Ling Wang, Hong Rui Song, Zhi Qiang Feng, Lei Lei, Quan Liu, Zhu Fang Shen,