Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1257888 | Chinese Chemical Letters | 2011 | 4 Pages |
Abstract
The DNA nuclease-like activity of a water soluble manganese corrole 5, 10, 15-tris(N-methyl-4-pyridyl)- corrolatomanganese(III) (MnIIITMPyC) has been investigated. MnIIITMPyC may bind strongly to DNA via outside groove binding mode as indicated by absorption spectra, viscosity measurements and CD spectra. MnIIITMPyC exhibited excellent catalytic activity in the DNA oxidative cleavage in the presence of hydroperoxide.
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Authors
Jun Lu, Hai Yang Liu, Lei Shi, Xiang Li Wang, Xiao Ying, Lei Zhang, Liang Nian Ji, Lin Quan Zang, Chi K. Chang,